The NIHR cognitive health Clinical Research Facility (CH-CRF) at the Warneford Hospital is hosted by Oxford Health NHS Foundation Trust. It is one of the 23 Clinical Research Facilities supported by the NIHR. Skilled staff advise on and support delivery of complex, high intensity experimental research with the aim of speeding up the translation of scientific advances for the benefit of patients.
The CH-CRF works in partnership with Oxford Health and the University of Oxford and is aligned with the strategies for both the Oxford Health Biomedical Research Centre and Oxford Biomedical Research Centre (BRC). The CRF provides a flexible, integrated neuroscience resource that facilitates efficient, timely conduct of experimental neuroscience enabling high intensity, early phase experimental medicine (EM) and research.
Main research areas include dementia and adult mental health, with a focus on mood disorders. Examples of current studies include: the European Prevention of Alzheimer’s Dementia (EPAD), a research ready cohort study in preparation for testing new treatments for dementia; studies that use an experimental medicine model to investigate a potential new treatment for depression and an early phase study aiming to test a new approach using immunotherapy in people with acute symptoms of psychosis. Integrated mood disorders clinics provide further research opportunities for patients.
An exciting new development is the integration of the CH – CRF with the Oxford Health BRC Brain Health Centre (based at the Oxford Centre for Human Brain Activity), a new integrated research and clinical environment providing high-quality assessments for patients with memory problems. The aim is to improve diagnosis and management in a way that can be rapidly integrated by the wider health service leading to improved care.
The CH-CRF is underpinned by state-of-the–art facilities at the Warneford and John Radcliffe Hospitals, including The Wellcome Centre for Integrative Neuroimaging of which the Oxford Centre for Human Brain Activity (OHBA) is a part.
Embedded within the local and national neuroscience community our CH-CRF is uniquely positioned to deliver high intensity experimental medicine leading to improved treatments for patients
Our building is located to the left of the main reception at the Warneford Hospital.
NIHR Oxford cognitive health Clinical Research Facility
Warneford Hospital, Warneford Lane
Headington, Oxford, OX3 7JX
Telephone: 01865 902 135