The University of Oxford: Centre for Human Genetics, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN
Research Grade 7: £39,424 – £43,984 per annum. This is inclusive of a pensionable Oxford University Weighting of £1,730 per year.
The University of Oxford is seeking to appoint a Postdoctoral Researcher in Neuroscience to play a central role in a Wellcome-funded translational research programme focused on understanding how immune mechanisms contribute to psychiatric disorders. This post offers an exciting opportunity contribute directly to translating fundamental biological discoveries into therapeutic strategies, within a world-leading research environment at the University of Oxford.
The programme integrates patient stratification using cerebrospinal fluid biomarkers, patient-derived induced pluripotent stem cell (iPSC) models, and pharmacological modulation of disease-relevant cellular readouts. The postholder will lead major experimental workstreams within the programme, taking responsibility for experimental design, data generation, and integration. Prior experience with iPSC-based neuronal and glial differentiation is essential. Experience with multi-electrode array (MEA) methodologies and multi-omic approaches (e.g. single-cell transcriptomics or proteomics) would be an advantage.
The postholder will join the Oxford Laboratory for Neuroimmunology and Immunopsychiatry, led by Associate Professor Lahiru Handunnetthi. The group focuses on understanding how immune mechanisms contribute to brain health disorders, using human stem-cell-derived models, multi-omic approaches, and clinically informed experimental designs. The work is embedded within a strong translational ecosystem, with close collaboration with clinical teams, the NIHR Oxford Health Biomedical Research Centre, and the Centre for Medicines Discovery. The postholder will work closely with Professors Paul Harrison, Rachel Upthegrove, and Emma Mead.
The postholder will receive strong mentorship and support for professional development, including training in new experimental and analytical techniques, opportunities to supervise students, and involvement in manuscript preparation and future grant applications.
This listing will expire at 12:00pm on Monday 16th February 2026
