Dr Dominic O’Connor, Research Associate at the University of Manchester, is working with the NIHR Mental Health Translational Research Collaboration (MH-TRC) Mission’s Children and Young People’s Mental Health workstream to explore the experiences of children who have been adopted through local authority care in the UK.
The E-LAB study is an examination of the relationship between childhood trauma, neurodevelopmental disorders, mental health, immune function and cognitive processes.
Dr O’Connor spoke recently about the new study:
Early life experiences shape who we become, influencing not only our immediate development, but also casting long shadows into adulthood.
The relationship between childhood trauma, mental health, and brain development is complex and multifaceted, yet understanding these connections is crucial for developing effective interventions that can change lives.
This is the driving force behind our groundbreaking research initiative: the E-LAB Study.
Research has consistently shown that adverse childhood experiences can have profound effects on brain development, emotional regulation, and cognitive functioning. However, the mechanisms underlying these relationships are not fully understood.
By examining how childhood trauma intersects with neurodevelopmental differences, mental health outcomes, cognitive development and immune system responses, we aim to build a comprehensive picture that can guide more effective support strategies for young people.
Our innovative modular approach, co-designed with parent contributors from the Parents of Traumatised Adopted Teens Organisation (POTATO) , makes participation accessible for young people with complex social and emotional needs. Unlike traditional research that can create barriers, we offer:
- Flexible participation – combining online and in-person assessments that work around your schedule.
- Five interconnected modules designed to minimize burden while capturing the full adolescent experience.
- Participant-centred approach – the study fits your life, not the other way around.
Recruitment for the E-LAB study is currently ongoing, and we’re actively seeking adolescents aged 13-17 years, who were adopted from UK local authority care, and their consenting parents or guardians to participate in this important research.
Read Dr O’Connor’s article in full on the University of Manchester website to learn more about E-LAB.
For more information and to apply to take part email mhmpsych@manchester.ac.uk
