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NIHR Oxford Health Biomedical Research Centre

Improving brain health: the future in mind

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Core facilities

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Clinical services and research are conveniently co-located at the Warneford Hospital site, and at the nearby Old Road Campus. Core facilities include:

NIHR Oxford cognitive health Clinical Research Facility (NIHR Oxford CH- CRF)
Oxford Centre for Human Brain Activity (OHBA)
Case Records Interactive Search (CRIS)
Oxford Centre for Anxiety Disorders and Trauma (OxCADAT)

Complementary facilities

The facilities on the Warneford Hospital site are complemented by leading neuroimaging facilities and expertise close at hand, including:

► Oxford Acute Vascular Imaging Centre (AVIC)


AVIC at Oxford’s John Radcliffe Hospital is a facility dedicated to clinical research in acute coronary syndromes (heart attack and unstable angina) and stroke and TIA. Its facilities below are uniquely conjoined:

  • 3T MRI scanner
  • Interventional angiography suite

► Oxford Centre for Functional MRI of the Brain (FMRIB) / Wellcome Centre for Integrative Neuroimaging


FMRIB / Wellcome Centre for Integrative Neuroimaging is based within the Nuffield Department of Clinical Neurosciences and sited at Oxford’s John Radcliffe Hospital. FMRIB is a multi-disciplinary neuroimaging research facility comprising:

  • Magnetic Resonance Imaging (MRI)
  • Electroencephalography (EEG)
  • Non-invasive brain stimulation

Collaborators and platforms

Our work is supported by these pioneering and innovative research groups and networks:

► The Structural Genomics Consortium (SGC)


SGC is a large public-private partnership (six academic institutions, five public bodies/charities and eight pharma companies) that supports the discovery of new medicines using open science.  Based on the Old Road Campus, a five minute walk from the NIHR Oxford Health BRC’s Warneford site, it is creating a new drug discovery ecosystem, supporting mental health treatments.

► MRC Dementias Platform UK (DPUK)


Dementias Platform UK is a public-private partnership funded by the Medical Research Council. DPUK’s partners – ten universities and six pharmaceutical companies – have joined forces with the aim of accelerating research towards effective treatment for dementia by improving access to data. By bringing together records from over 40 different cohort studies – including brain scans, genetics and clinical records – DPUK is creating the world’s richest source of people data for use in research and drug development for dementia.

This free-to-access resource of cohort data, the Data Portal, is available for use by any bona fide researcher who is interested in investigating dementia whether based within a university or industry context. DPUK facilitates safe and secure access to this data through its Data Portal, enabling research and analyses at a scale that has not previously been possible for studies into dementia. It wishes to promote scientific research using cohort study data, and has an active programme of experimental medicine.

► Alzheimer’s Research UK Drug Discovery Institute Oxford (ARUK DDI Oxford)


ARUK DDI Oxford is a £10 million investment that combines deep disease knowledge and biological expertise with high quality, innovative drug discovery technologies to deliver new therapies for dementia. The DDI is based in the Target Discovery Institute, Nuffield Department of Medicine at the University of Oxford, Old Road Campus.

► Improving Access to Psychological Therapies (IAPT)


IAPT, led by Professor David Clarke at the University of Oxford, has been rolled out across the NHS to ensure that patients access help more quickly and easily for common mental health problems.

Watch this video about IAPT.

► NIHR Oxford University Hospitals Biomedical Research Centre (OUH BRC)

We will work closely with our colleagues at the OUH BRC, particularly in some of their core themes:

  • Preventative Neurology
  • Imaging

► National Biomedical Research Centres

We will work closely with other mental and brain health  themes in national BRCs. Together we will transform the strategic outlook for mental health research in the UK. We aim to

  • integrate systems for patient access to research.
  • create state-of-the-art infrastructure for experimental medicine in mental health.
  • optimise the training and career development opportunities available to future leaders of therapeutic progress.

► Oxford Academic Health Partners  (OAHP)

OAHP coordinates clinical and academic excellence within Oxford University, Oxford Brookes University, Oxford Health NHS Foundation Trust and Oxford University Hospitals NHS Foundation Trust.

► Oxford Academic Health Science Network (Oxford AHSN)

Oxford AHSN consolidates interactions between Oxford universities, hospitals and industry networks to create new therapeutics, diagnostics, devices, companies and jobs.

► NIHR Applied Research Collaboration Oxford and Thames Valley (NIHR ARC OxTV)

NIHR ARC Oxford and Thames Valley is hosted by Oxford Health NHS Foundation Trust. It has a strong emphasis on mental health and primary care. The ARC carries out applied health and social care research intended to solve practical problems and works across local infrastructure. This joint working ensures pull through from discovery science to implementation.
Find out more.

► NIHR Clinical Research Network: Thames Valley and South Midlands (NIHR CRN)

NIHR CRN is the clinical research delivery arm of the NHS. The NIHR CRN: Thames Valley and South Midlands is hosted by Oxford University Hospitals NHS Foundation Trust.

The NIHR Oxford Health BRC is also supported by:

Oxford StemBANCC
Target Discovery Institute (TDI)
Big Data Institute (BDI)
UK Biobank
Kennedy Institute
Wellcome Trust Centre for Human Genetics
BioEscalator

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About the NIHR Oxford Health Biomedical Research Centre

  • About
  • Management and core team
    • Profile: John Geddes – Oxford Health BRC Director
    • Profile: Nick Broughton – Oxford Health BRC Chair, Steering Committee
    • Profile: Bill Wells – Oxford Health BRC Finance Manager
  • Our partners
  • Timeline of our key achievements
  • Core facilities
  • Oxford Centre for Human Brain Activity
  • Clinical Record Interactive Search – NIHR Oxford Health Biomedical Research Centre
  • Work with us
  • Contact

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Improving brain health: the future in mind

The National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) is a partnership between Oxford Health NHS Foundation Trust and the University of Oxford.  We are part of the Oxford Academic Health Partners.
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