Theme leads
Research Focus
This research programme is dedicated to advancing the understanding and treatment of Sleep and Circadian Rhythm Disorders (SCRD) through the application of cutting-edge science and translational innovation. SCRD are prevalent, costly, and negatively impact mental and physical health. The programme aims to develop, test, and implement scalable, cost-effective interventions that can improve health outcomes and quality of life for individuals affected by SCRD.
Regional Context
The primary research activities will be based in Oxford, with strategic collaboration from the Universities of Surrey and Manchester. This tri-institutional partnership brings together a high level of expertise in sleep science, chronobiology, and clinical research. The collaboration is uniquely positioned to address the high prevalence and complexity of SCRD across diverse populations, including those affected by occupational factors such as shift work. The regional distribution of research sites also enhances the capacity for multicentre trials, ensures diversity in patients and participants, and broadens the potential for national impact.
Research Aims
The overarching aim is to establish an interdisciplinary research team capable of delivering innovative solutions to SCRD. The programme will focus on the development, evaluation, and translation of novel interventions that are both clinically effective and economically viable. Specific objectives include:
- Conducting a fully funded, multicentre randomised controlled trial targeting shift work sleep disorder. This trial will evaluate new components of a complex intervention, alongside novel monitoring tools and outcome measures, with the goal of informing future clinical trials and practice.
- Generating pilot data through targeted pump-priming initiatives. The funds are being used to support exploratory studies in areas such as behavioural therapeutics, chrono nutrition, light environment and novel sleep monitoring methods. The intention is to develop at least one new therapeutic approach for SCRD.
- Building research capacity by supporting the career development of clinician-researchers in this field. Early-career investigators are encouraged to apply for pump-priming funding to initiate independent lines of inquiry and contribute to the programme’s long-term sustainability. We also offer grants to NMAHPs and NHS psychologists/psychiatrists to study on our various training programmes: MSc/PGDip in Sleep medicine and masterclasses in cognitive behavioural therapy for insomnia and in sleep measurement.
Impact
This research programme is designed to bridge the gap between fundamental sleep and circadian science and real-world clinical application. By focusing on scalable and cost-effective interventions, the work aims to deliver tangible improvements in patient care and public health. The emphasis on shift work sleep disorder addresses a critical occupational health issue, with implications for workforce productivity, safety, and wellbeing. Furthermore, the integration of novel technologies and methodologies will enhance the precision and effectiveness of future interventions.
Through its interdisciplinary approach and strong institutional collaboration, this programme is poised to make a significant contribution to the field of sleep and circadian health, with the potential to influence clinical guidelines, inform policy, and improve outcomes for individuals across the UK and beyond.
