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Depression Therapeutics

Accelerating discovery of novel treatments using neurocognitive experimental medicine models

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News for the Depression Therapeutics theme

New study for Treatment-Resistant Depression launches at Oxford Health Clinical Research Facility

17th October 2024

Recently, the NIHR Oxford Health Clinical Research Facility (OH CRF) has begun researching a new potential drug treatment for Treatment-Resistant Depression (TRD). A significant number of people with depression are not…

OH BRC Director Designate honoured in the Kings birthday honours list 2024

8th October 2024

We would like to congratulate our esteemed colleague Professor Rachel Upthegrove MBE, MBBS, FRCPsych, PhD on her recent achievement of receiving the Member of the Order of the British Empire…

Reflections – New Therapeutic Approaches in Translational Mental Health Conference

2nd October 2024

The New Therapeutic Approaches in Translational Mental Health Conference was held on 16 September 2024 at the Mathematical Institute in Oxford. The event was organised by Betina Nair and Dr…

Would you like to join the Diversity in Research group?

19th September 2024

NIHR Oxford Health Biomedical Research Centre (OH BRC) and NIHR Oxford Biomedical Research Centre are seeking committed individuals to join their Diversity in Research Group to share experiences and ideas…

New study – Serotonin changes how people learn and respond to negative information

9th August 2024

Increasing serotonin can change how people learn from negative information, as well as improving how they respond to it, according to a new study published in the leading journal Nature…

Could taking a specific anticonstipation drug reduce your risk of depression?

8th August 2024

In a new paper published today in BJPsych it is suggested that a specific anti constipation drug, prucalopride may reduce the risk of experiencing depression in individuals with no past…

Open Day at Westgate Centre showcases Oxford’s groundbreaking research

17th July 2024

Recently, visitors to Oxford’s Westgate Centre were able to learn about the world-class healthcare research taking place in the city. The annual Biomedical Research Centre (BRC) Open Day, hosted by…

Professor Rachel Upthegrove made MBE

17th June 2024

Professor Rachel Upthegrove, who joins the University of Oxfords Department of Psychiatry and our BRC as Director Designate in August, has been made an MBE in the King’s Birthday Honours…

AI to help personalise treatment for depression in Oxfordshire as part of major trial

13th May 2024

People with depression are being invited to be part of a clinical trial testing a new evidence-based AI treatment tool to personalise antidepressant treatment. The revolutionary digital tool, called PETRUSHKA,…

Joint Oxford Health and Oxford BRC Open Day: Shaping the Future of Healthcare

26th April 2024

Come and join us for our BRC Open Day at the Westgate Centre in Oxford between 10am and 3.30pm on Thursday 30 May. The event – held jointly with Oxford…

Oxford Health BRC Workshop – Inclusive research & exclusion criteria

28th March 2024

Recently, the OH BRC held a Joint Equality Diversity and Inclusion (EDI) & Patient and Public Involvement Engagement and Participation (PPIEP) workshop in Oxford to discuss barriers to research participation,…

Professor Rachel Upthegrove appointed Director Designate of the Oxford Health BRC

14th March 2024

We are delighted to announce that Professor Rachel Upthegrove has been appointed as the new director designate and Senior Clinical Researcher of the Oxford Health Biomedical Research Centre (OH BRC)…

NIHR MH-TRC Mental Health Mission Research Posts Award Scheme 2024

8th February 2024

Opportunity for research posts that align with the Mental Health Mission Work Packages, and Demonstrator sites. Deadline for application: 1 March 2024 Queries to MHM-capacity@manchester.ac.uk. MHM Work Packages Capacity development…

Research in the University of Oxford Department of Psychiatry 2023

17th January 2024

Associate Head of Department for Research and Oxford Health Biomedical Research Centre (OH BRC) Theme lead for Molecular Targets Professor Paul Harrison outlines the research highlights of 2023 in this…

Welcome to new colleagues in the OH BRC core team

16th January 2024

In recent months the core team at OH BRC has expanded and we would like to welcome our new colleagues to the team. Cora Reilly-McGeown Patient and Public Involvement, Engagement…

Next step in plans for Warneford Park

8th January 2024

Plans for Warneford Park took a step forward as partners in the project signed a Conditional Option Agreement (COA) and Memorandum of Understanding (MOU), agreeing how they will work together…

Mental Health Mission for mental health research – who is involved?

12th December 2023

Birmingham Health Partners (BHP) members, the University of Birmingham, Birmingham Women’s and Children’s NHS Foundation Trust and Birmingham & Solihull Mental Health NHS Foundation Trust, alongside Oxford Health Biomedical Research…

Innovation Perspectives: Q&A with Professor John Geddes

12th December 2023

This morning the Oxford Academic Health Partners (OAHP) published an interview with NIHR Oxford Health Biomedical Research Centre Director Prof John Geddes. In the interview, Prof Geddes discusses the NIHR…

Call for more research investment for serious mental illness treatments.

7th December 2023

More focused research on medication for serious mental illness is needed in the UK according to a leading Oxford Professor. Oxford University Professor Husseini Manji, global leader in the development…

New treatment development for Serious Mental Illness

6th December 2023

A global leader in the development of new medications for patients with serious mental illness discussed recently what needs to be done to make a real difference in their treatment….

The Cognitive Remediation in Bipolar Disorder study (CRiB2) is looking for participants

16th November 2023

The CRiB2 study is investigating the effects of a new psychological therapy for people with bipolar disorder and is looking for volunteers to take part in the study. Are you…

University of Oxford Awarded £3 Million to Establish HealthTech Research Centre

14th November 2023

Oxford Health NHS Foundation Trust wins NIHR award for new HealthTech Research Centre (HRC) to explore innovative Health Technology to enhance community and primary care. The University of Oxford’s Nuffield Department…

Can statins enhance the effects of antidepressants in treating depression?

9th November 2023

Researchers including Oxford Health Biomedical Research Centre (OH BRC) Theme Leads Philip Cowen, Catherine Harmer and Andrea Cipriani led a recent study funded by the Wellcome Trust and the OH…

A new approach to recruiting for clinical trials

7th November 2023

‘Count Me In’: Transforming research practice in mental healthcare through a novel recruitment approach that offers access to a large and diverse patient cohort. Dr Verena Hinze writes about her new study…

New NIHR campaign “Shape the Future” how to get involved.

7th November 2023

Staff are encouraged to learn more about a career in research through The Shape the Future campaign launched this month by the National Institute for Health and Care Research (NIHR)….

Tackling mental illness by supporting industry to develop new drugs

13th October 2023

Did you know mental illnesses such as depression are a leading cause of disability? And there is huge unmet demand for drugs to treat psychiatric disorders. In recognition of World…

Stop Press- launch of Oxford Health BRC Senior Fellowships

12th October 2023

The NIHR Oxford Senior Research Fellows Award scheme recognises and supports individuals with the potential and trajectory to become future leaders in translational research in the NIHR in Oxford. This…

Celebrating another successful year of biomedical research

10th October 2023

Developments and improvements to the treatment and knowledge of conditions including depression, dementia and psychosis were in the spotlight at a recent event in Oxford. National Institute of Health and…

ORAG (ORIGIN Research Advisory Group) – Shape the future of research – Opportunity for 16–24-year-olds

3rd October 2023

ORIGIN aims to have a positive impact on the mental health of 16–24-year-olds. The research is led by Dr Rebecca Syed Sheriff at the University of Oxford and builds on very promising…

Prestigious International Mental Health prize awarded to Oxford University Professor

29th September 2023

The National Academy of Medicine (NAM) recently announced that Oxford University Professor Husseini Manji and his colleagues Dennis Charney and John Krystal, are the recipients of the 2023 Rhoda and Bernard…

Number of people taking part in life-changing research reaches almost one million

29th June 2023

Participation in health and care research It has been another successful year for participation in health and care research, with almost one million participants across England taking part in NIHR research…

More than £96m awarded to NHS for cutting-edge research equipment

28th June 2023

Cutting-edge research equipment and technology The NIHR has awarded more than £96 million to 93 NHS organisations across England, which are all part of the NIHR’s wider infrastructure. This includes…

NIHR INSIGHT: Inspiring Students into Research Round 1

21st June 2023

The INSIGHT: Inspiring Students into Research scheme aims to attract students in registered healthcare, social work and public health professions (not including doctors and dentists) into the full range of…

Sign up to be contacted about taking part in health research studies

7th June 2023

People interested in taking part in health research studies are being encouraged to sign up to a new service which notifies them about trials they could join. More than 150,000…

Oxford Health plays a leading role in £42.7m research effort to find innovative new treatments for mental illness

26th May 2023

Research with the potential to change the lives of millions around the world suffering with mental illness has received a boost with the announcement of £42.7m of government funding. Clinicians…

Westgate Centre visitors learn about Oxford’s ground-breaking research

12th May 2023

Hundreds of visitors to Oxford’s Westgate Centre on Wednesday 10 May were able to find out about the world-class healthcare research that is currently taking place in Oxford. The Westgate’s…

£3 million legacy gift to deliver significant benefits for people with bipolar disorder

30th March 2023

Research into bipolar disorder at Oxford has received a major boost following a £3 million donation from the Page family. The legacy gift will support the development of innovative new…

£35.4m to transform mental and brain health care across the UK – and the world

14th October 2022

Innovative treatments and transformative therapies in brain health are on the horizon thanks to a £35.4 million award to the NIHR Oxford Health Biomedical Research Centre. The award, announced on…

Analysis of antidepressant dosage highlights need for new clinical guidelines

27th June 2019

Analysis published earlier this month in The Lancet Psychiatry shows that a lower dose of the most commonly used second-generation antidepressants achieves the best balance of effectiveness and tolerability in…