Recent Publications – Adult Mental Health Al-Diwani A, Handel A, Townsend L, Pollak T, Leite MI, Harrison PJ, Lennox BR, Okai D, Manohar SG, Irani SR. The psychopathology of NMDAR-antibody encephalitis in adults: a systematic review and phenotypic analysis of individual patient data. Lancet Psychiatry. 2019 Mar;6(3):235-246. Atkinson, L.Z., Colbourne, L., Smith, A. et al. The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study. Trials 20, 120 (2019). Bauer M, Andreassen OA, Geddes JR, Vedel Kessing L, Lewitzka U, Schulze TG, et al. Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives. Lancet Psychiatry. 2018 Aug 23; Bauer M, Monteith S, Geddes J, Gitlin MJ, Grof P, Whybrow PC, Glenn T. Automation to optimise physician treatment of individual patients: examples in psychiatry. Lancet Psychiatry. 2019 Apr;6(4):338-349. Bighelli I, Castellazzi M, Cipriani A, Girlanda F, Guaiana G, Koesters M, Turrini G, Furukawa TA, Barbui C. Antidepressants versus placebo for panic disorder in adults. Cochrane Database of Systematic Reviews. 2018(4). Breilmann J, Girlanda F, Guaiana G, Barbui C, Cipriani A, Castellazzi M, Bighelli I, Davies SJ, Furukawa TA, Koesters M. Benzodiazepines versus placebo for panic disorder in adults. Cochrane Database of Systematic Reviews. 2019(3). Cavanagh SE, Towers JP, Wallis JD, Hunt LT, Kennerley SW. Reconciling persistent and dynamic hypotheses of working memory coding in prefrontal cortex. Nat Commun. 2018 Aug 29;9(1):3498. Cipriani A, Salanti G, Furukawa TA, Egger M, Leucht S, Ruhe HG, et al. Antidepressants might work for people with major depression: where do we go from here? Lancet Psychiatry. 2018 Jun;5(6):461–3. Cipriani A, Williams T, Nikolakopoulou A, Salanti G, Chaimani A, Ipser J, et al. Comparative efficacy and acceptability of pharmacological treatments for post-traumatic stress disorder in adults: a network meta-analysis. Psychol Med. 2018 Sep;48(12):1975–84. Cortese S, Adamo N, Del Giovane C, Mohr-Jensen C, Hayes AJ, Carucci S, et al. Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis. Lancet Psychiatry. 2018 Sep;5(9):727–38. Davies C, Cipriani A, Ioannidis JP, Radua J, Stahl D, Provenzani U, McGuire P, Fusar-Poli P. Lack of evidence to favor specific preventive interventions in psychosis: a network meta-analysis. World Psychiatry. 2018 Jun;17(2):196-209. Davies C, Radua J, Cipriani A, Stahl D, Provenzani U, McGuire P, Fusar-Poli P. Efficacy and acceptability of interventions for attenuated positive psychotic symptoms in individuals at clinical high risk of psychosis: a network meta-analysis. Frontiers in psychiatry. 2018;9. De Crescenzo F, Ciabattini M, D’Alò GL, De Giorgi R, Del Giovane C, Cassar C, Janiri L, Clark N, Ostacher MJ, Cipriani A. Comparative efficacy and acceptability of psychosocial interventions for individuals with cocaine and amphetamine addiction: A systematic review and network meta-analysis. PLoS medicine. 2018 Dec 26;15(12):e1002715. Duffy A, Heffer N, Goodday SM, Weir A, Patten S, Malhi GS, et al. Efficacy and tolerability of lithium for the treatment of acute mania in children with bipolar disorder: A systematic review: A report from the ISBD-IGSLi joint task force on lithium treatment. Bipolar Disord. 2018 Sep 16; Duffy A, Keown-Stoneman CD, Goodday SM, Saunders K, Horrocks J, Grof P, Weir A, Hinds C, Geddes J. Daily and weekly mood ratings using a remote capture method in high-risk offspring of bipolar parents: Compliance and symptom monitoring. Bipolar Disord. 2019 Mar;21(2):159-167. Epub 2018 Dec 12. Duffy A, Saunders KEA, Malhi GS, Patten S, Cipriani A, McNevin SH, MacDonald E, Geddes J. Mental health care for university students: a way forward? Lancet Psychiatry. 2019 Jul 16. pii: S2215-0366(19)30275-5. Duthie A, van Aalten L, MacDonald C, McNeilly A, Gallagher J, Geddes J, Lovestone S, Sutherland C. Recruitment, Retainment, and Biomarkers of Response; A Pilot Trial of Lithium in Humans With Mild Cognitive Impairment. Front Mol Neurosci. 2019 Jun 28;12:163. Faurholt-Jepsen M, Geddes JR, Goodwin GM, Bauer M, Duffy A, Vedel Kessing L, Saunders K. Reporting guidelines on remotely collected electronic mood data in mood disorder (eMOOD) -recommendations. Transl Psychiatry. 2019 Jun 7;9(1):162. Freeman TP, Mehta MA, Neill JC, Nutt DJ, Tunbridge EM, Young AH. Restrictions on drugs with medical value: Moving beyond stalemate. J Psychopharmacol. 2018 Oct;32(10):1053-1055. Freeman D, Yu LM, Kabir T, Martin J, Craven M, Leal J, Lambe S, Brown S, Morrison A, Chapman K, Dudley R, O’Regan E, Rovira A, Goodsell A, Rosebrock L, Bergin A, Cryer TL, Robotham D, Andleeb H, Geddes JR, Hollis C, Clark DM, Waite F. Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial(gameChange). BMJ Open. 2019 Aug 27;9(8):e031606. Gobbi G, Atkin T, Zytynski T, Wang S, Askari S, Boruff J, Ware M, Marmorstein N, Cipriani A, Dendukuri N, Mayo N. Association of cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: a systematic review and meta-analysis. JAMA psychiatry. 2019 Feb 13. Goodday SM, Rivera D, Foran H, King N, Milanovic M, Keown-Stoneman CD, Horrocks J, Tetzlaff E, Bowie CR, Pickett W, Harkness K, Saunders KE, Cunningham S, McNevin S, Duffy A. U-Flourish university students well-being and academic success longitudinal study: a study protocol. BMJ Open. 2019 Aug 26;9(8):e029854. Gordon-Smith K, Saunders K, Geddes JR, Harrison PJ, Hinds C, Craddock N, Jones I, Jones L. Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network. J Affect Disord. 2019 Mar 1;246:789-793. Harrison PJ. D-Amino Acid Oxidase Inhibition: A New Glutamate Twist for Clozapine Augmentation in Schizophrenia? Biol Psychiatry. 2018 Sep 15;84(6):396–8. Harrison PJ, Colbourne L, Harrison CH. The neuropathology of bipolar disorder: systematic review and meta-analysis. Mol Psychiatry. 2018 Aug 20; Harrison PJ, Tunbridge EM, Dolphin AC, Hall J. Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal. Br J Psychiatry. 2019 Jun 24:1-4. Hui TP, Kandola A, Shen L, Lewis G, Osborn DPJ, Geddes JR, Hayes JF. A systematic review and meta-analysis of clinical predictors of lithium response in bipolar disorder. Acta Psychiatrica Scand. 2019 Aug;140(2):94-115. Hunt LT, Malalasekera WMN, de Berker AO, Miranda B, Farmer SF, Behrens TEJ, et al. Triple dissociation of attention and decision computations across prefrontal cortex. Nat Neurosci. 2018 Oct;21(10):1471–81. Leucht S, Chaimani A, Leucht C, Huhn M, Mavridis D, Helfer B, et al. 60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia: Meta-regression of predictors of placebo response. Schizophr Res. 2018 May 24; Martens MA, Antley A, Freeman D, Slater M, Harrison PJ, Tunbridge EM. It feels real: physiological responses to a stressful virtual reality environment and its impact on working memory. J Psychopharmacol. 2019 Oct;33(10):1264-1273. McShane R, Westby MJ, Roberts E, Minakaran N, Schneider L, Farrimond LE, Maayan N, Ware J, Debarros J. Memantine for dementia. Cochrane Database Syst Rev. 2019 Mar 20;3:CD003154. McGowan NM, Goodwin GM, Bilderbeck AC, Saunders KEA. Circadian rest-activity patterns in bipolar disorder and borderline personality disorder. Translational Psychiatry. 2019 Aug 20;9(1):195. Nickless A, Voysey M, Geddes J, Yu LM, Fanshawe TR. Mixed effects approach to the analysis of the stepped wedge cluster randomised trial-Investigating the confounding effect of time through simulation. PLoS One. 2018 Dec 13;13(12):e0208876. Palmius N, Saunders KEA, Carr O, Geddes JR, Goodwin GM, De Vos M. Group-Personalized Regression Models for Predicting Mental Health Scores From Objective Mobile Phone Data Streams: Observational Study. J Med Internet Res. 2018 Oct 22;20(10):e10194. Patel S, Saunders KE. Apps and wearables in the monitoring of mental health disorders. Br J Hosp Med (Lond). 2018 Dec 2;79(12):672-675. Perez Arribas I, Goodwin GM, Geddes JR, Lyons T, Saunders KEA. A signature-based machine learning model for distinguishing bipolar disorder and borderline personality disorder. Transl Psychiatry. 2018 Dec 13;8(1):274. Severus E, Bauer M, Geddes J. Efficacy and Effectiveness of Lithium in the Long-Term Treatment of Bipolar Disorders: An Update 2018. Pharmacopsychiatry. 2018 Sep;51(5):173-176 Shalev N, Vangkilde S, Neville MJ, Tunbridge EM, Nobre AC, Chechlacz M. Dissociable Catecholaminergic Modulation of Visual Attention: Differential Effects of Catechol-O-Methyltransferase and Dopamine Beta-Hydroxylase Genes on Visual Attention. Neuroscience. 2019 Aug 1;412:175-189. Sheaves B, Holmes EA, Rek S, Taylor KM, Nickless A, Waite F, Germain A, Espie CA, Harrison PJ, Foster R, Freeman D. Cognitive Behavioural Therapy for Nightmares for Patients with Persecutory Delusions (Nites): An Assessor-Blind, Pilot Randomized Controlled Trial. Can J Psychiatry. 2019 May 26:706743719847422. Simon J, Geddes JR, Gardiner A, Rendell J, Goodwin GM, Mayer S. Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL). Bipolar Disord. 2018 Dec;20(8):733-745. Singh N, McMahon H, Bilderbeck A, Reed ZE, Tunbridge E, Brett D, et al. Plasma glutathione suggests oxidative stress is equally present in early- and late-onset bipolar disorder. Bipolar Disord. 2018 Mar 30; Smith KA, Cipriani A, Hawton KE. Modelling suicide in bipolar disorders: Limitations and opportunities. Bipolar Disord. 2018 Sep;20(6):566–7. Soliman E, Ranjan S, Xu T, Gee C, Harker A, Barrera A, Geddes J. A narrative review of the success of intramuscular gluteal injections and its impact in psychiatry. Biodes Manuf. 2018;1(3):161-170 Tunbridge EM, Narajos M, Harrison CH, Beresford C, Cipriani A, Harrison PJ. Which Dopamine Polymorphisms Are Functional? Systematic Review and Meta-analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1, and VMAT2. Biol Psychiatry. 2019 Oct 15;86(8):608-620. Veraart JKE, Smith-Apeldoorn SY, Trueman H, de Boer MK, Schoevers RA, McShane R. Characteristics of patients expressing an interest in ketamine treatment: results of an online survey. BJPsych Open. 2018 Sep 5;4(5):389-392. Vidaurre D, Hunt LT, Quinn AJ, Hunt BAE, Brookes MJ, Nobre AC, Woolrich MW. Spontaneous cortical activity transiently organises into frequency specific phase-coupling networks. Nat Commun. 2018 Jul 30;9(1):2987. Walsh A, Matini L, Hinds C, Sexton V, Brain O, Keshav S, Geddes J, Goodwin G, Collins G, Travis S, Peters M. Real-time data monitoring for ulcerative colitis: patient perception and qualitative analysis. Intest Res. 2019 Jul;17(3):365-374. Walsh A, Kormilitzin A, Hinds C, Sexton V, Brain O, Keshav S, Uhlig H, Geddes J, Goodwin G, Peters M, Collins G, Travis S. Defining Faecal Calprotectin Thresholds as a Surrogate for Endoscopic and Histological Disease Activity in Ulcerative Colitis-a Prospective Analysis. J Crohns Colitis. 2019 Mar 30;13(4):424-430. Ward J, Tunbridge EM, Sandor C, Lyall LM, Ferguson A, Strawbridge RJ, Lyall DM, Cullen B, Graham N, Johnston KJA, Webber C, Escott-Price V, O’Donovan M, Pell JP, Bailey MES, Harrison PJ, Smith DJ. Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Mol Psychiatry. 2019 Jul 30. Wu S, Gao L, Cipriani A, Huang Y, Yang Z, Yang J, Yu S, Zhang Y, Chai S, Zhang Z, Sun F. The effects of incretin based therapies on cell function and insulin resistance in type 2 diabetes: A systematic review and network meta?analysis combining 360 trials. Diabetes, Obesity and Metabolism. 2019 Apr;21(4):975-83. Zhou X, Liu L, Lan X, Cohen D, Zhang Y, Ravindran AV, Yuan S, Zheng P, Coghill D, Yang L, Hetrick SE. Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and adolescents. Molecular psychiatry. 2018 Apr 20:1. Zhou X, Zhang Y, Furukawa TA, Cuijpers P, Pu J, Weisz JR, Yang L, Hetrick SE, Del Giovane C, Cohen D, James AC. Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis. JAMA psychiatry. 2019 Jan 1;76(1):41-50.