Precision medicine in psychiatry – a focus on treatment prediction in depression: a meta review
Summary
This is a meta-review to identify individual predictors of treatment effect of pharmacological, psychological, electroconvulsive and neuromodulatory treatments in unipolar depression. We also aim to identify, catalogue and evaluate clinical prediction models of treatment effect with a specific focus in unipolar depression, complemented by a non-systematic exploration of clinical prediction models used in other fields.
Team
Dr George Gillet, Department of Psychiatry, University of Oxford, Oxford, UK
Dr Anneka Tomlinson, Department of Psychiatry, University of Oxford, Oxford, UK
Dr Orestis Efthimiou, Institute of Social and Preventive Medicine, Bern, Switzerland
Prof. Andrea Cipriani, Department of Psychiatry, University of Oxford, Oxford, UK: Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford
Protocol
Gillet et al., Precision medicine in psychiatry – a focus on treatment prediction in depression: a meta review
Prospero
https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=141425
Sleep deprivation as a treatment for major depressive episodes: a systematic review and meta-analysis
Summary
To assess the efficacy, acceptability and tolerability of sleep deprivation in comparison to any other intervention for the acute and long-term treatment of major depressive episodes in unipolar or bipolar affective disorders.
Team
Dr Pamina Mitta, Department of Psychiatry, University of Oxford, Oxford, UK: Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford
Dr Anneka Tomlinson, Department of Psychiatry, University of Oxford, Oxford, UK
Dr Orestis Efthimiou, Institute of Social and Preventive Medicine, Bern, Switzerland
Prof. Andrea Cipriani, Department of Psychiatry, University of Oxford, Oxford, UK: Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford
Protocol
Mitta et al., Sleep deprivation as a treatment for major depressive episodes: a systematic review and meta-analysis
Prospero
Under review
